Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody.
A monoclonal antibody (MAb), 4D5, specifically recognising an extracellular epitope of the c-ErbB-2 protein, inhibited the growth of human gastric cancer overexpressing c-ErbB-2 severe combined immunodeficient (SCID) mice. This antibody also reduced the mass of established tumours xenografted into S...
Main Authors: | , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
1995
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033805/ |