Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions

Fibrosis, characterized by excessive extracellular matrix accumulation, is a common feature of many connective tissue diseases, notably scleroderma (systemic sclerosis). Experimental studies suggest that a complex network of intercellular interactions involving endothelial cells, epithelial cells, f...

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Bibliographic Details
Main Authors: Krieg, Thomas, Abraham, David, Lafyatis, Robert
Format: Online
Language:English
Published: BioMed Central|1 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072888/