The transcriptional cycle of HIV-1 in real-time and live cells
RNA polymerase II (RNAPII) is a fundamental enzyme, but few studies have analyzed its activity in living cells. Using human immunodeficiency virus (HIV) type 1 reporters, we study real-time messenger RNA (mRNA) biogenesis by photobleaching nascent RNAs and RNAPII at specific transcription sites. Thr...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064765/ |