Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia
Cells from patients with Fanconi anemia (FA), an inherited disorder that includes bone marrow failure and cancer predisposition, have increased sensitivity to oxidative stress through an unknown mechanism. We demonstrate that the FA group G (FANCG) protein is found in mitochondria. Wild-type but not...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2006
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064564/ |