The Fanconi anemia pathway and ubiquitin

Fanconi anemia (FA) is a rare genetic disorder characterized by aplastic anemia, cancer/leukemia susceptibility and cellular hypersensitivity to DNA crosslinking agents, such as cisplatin. To date, 12 FA gene products have been identified, which cooperate in a common DNA damage-activated signaling p...

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Bibliographic Details
Main Authors: Jacquemont, Céline, Taniguchi, Toshiyasu
Format: Online
Language:English
Published: BioMed Central 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106361/