The Fanconi anemia pathway and ubiquitin
Fanconi anemia (FA) is a rare genetic disorder characterized by aplastic anemia, cancer/leukemia susceptibility and cellular hypersensitivity to DNA crosslinking agents, such as cisplatin. To date, 12 FA gene products have been identified, which cooperate in a common DNA damage-activated signaling p...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
BioMed Central
2007
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106361/ |