The disintegrin and metalloproteinase ADAM12 contributes to TGF-β signaling through interaction with the type II receptor

The disintegrin and metalloproteinase ADAM12 contributes to TGF-β signaling through interaction with the type II receptor

Transforming growth factor-β (TGF-β) regulates a wide variety of biological processes through two types of Ser/Thr transmembrane receptors: the TGF-β type I receptor and the TGF-β type II receptor (TβRII). Upon ligand binding, TGF-β type I receptor activated by TβRII propagates signals to Smad prote...

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Bibliographic Details
Main Authors: Atfi, Azeddine, Dumont, Emmanuelle, Colland, Frédéric, Bonnier, Dominique, L'Helgoualc'h, Annie, Prunier, Céline, Ferrand, Nathalie, Clément, Bruno, Wewer, Ulla M., Théret, Nathalie
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064440/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064440/

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