A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma

A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma

Interferon-gamma (IFN-γ) is a pleiotropic cytokine that exerts anti-tumor and anti-osteoclastogenic effects. Although transcriptional and post-transcriptional regulation of IFN-γ is well understood, subsequent modifications of secreted IFN-γ are not fully elucidated. Previous research indicates that...

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Bibliographic Details
Main Authors: Kanzaki, Hiroyuki, Shinohara, Fumiaki, Suzuki, Maiko, Wada, Satoshi, Miyamoto, Yutaka, Yamaguchi, Yuuki, Katsumata, Yuta, Makihira, Seicho, Kawai, Toshi, Taubman, Martin A., Nakamura, Yoshiki
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004192/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004192/

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