β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination
Myelin is a multispiraled extension of glial membrane that surrounds axons. How glia extend a surface many-fold larger than their body is poorly understood. Schwann cells are peripheral glia and insert radial cytoplasmic extensions into bundles of axons to sort, ensheath, and myelinate them. Laminin...
Main Authors: | Nodari, Alessandro, Zambroni, Desirée, Quattrini, Angelo, Court, Felipe A., D'Urso, Alessandra, Recchia, Alessandra, Tybulewicz, Victor L.J., Wrabetz, Lawrence, Feltri, M. Laura |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064366/ |
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