TP53 gene mutations and protein accumulation in primary vaginal carcinomas.

Primary carcinomas from 46 patients were screened for TP53 alterations. Immunohistochemistry demonstrated nuclear TP53 protein accumulation in 22 (48%) cases using the polyclonal CM1 antiserum, whereas 15 (33%) cases showed positive nuclear staining with the mononuclear antibody PAb 1801. Constant d...

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Bibliographic Details
Main Authors: Skomedal, H., Kristensen, G., Helland, A., Nesland, J. M., Kooi, S., Børresen, A. L., Holm, R.
Format: Online
Language:English
Published: 1995
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034131/