TP53 allele loss, mutations and expression in malignant melanoma.
p53 alterations at the DNA, mRNA and protein levels were studied in tumour metastases sampled from 30 patients with malignant melanoma. Paraffin-embedded sections from these and an additional 12 patients were examined for the presence of p53 protein. TP53 gene aberrations were found in 7 of 30 (23%)...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1994
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968671/ |