Presence of a heterozygous substitution and its relationship to DT-diaphorase activity.
A point mutation in the mRNA of NADP(H): quinone oxidoreductase 1 (NQO1, DT-diaphorase) is believed to be responsible for reduced enzyme activity in the adenocarcinoma BE cell line. The present study examined nine cultured human non-cancerous fibroblast cell strains, five of which were from members...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
1995
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033894/ |