Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase).
NAD(P)H:quinone oxidoreductase (NQO1, EC 1.6.99.2) is an obligate two-electron reductase that can either bioactivate or detoxify quinones and has been proposed to play an important role in chemoprevention. We have previously characterized a homozygous point mutation in the BE human colon carcinoma c...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
1997
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222704/ |