Synthesis and secretion of albumin in rats during treatment with a carcinogenic dose of N-2-acetylaminofluorene.
The chronic administration of N-2-acetylaminofluorene (N-2-AAF) to rats causes a loss of hepatic cytoplasmic RNA, particularly from the endoplasmic-membrane fractions. At the end of the complete carcinogenic dose, the level of amino-acid incorporation into proalbumin is normal, despite the loss of 3...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
1979
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010110/ |