Analysis at the sequence level of mutations induced by the ultimate carcinogen N-acetoxy-N-2-acetylaminofluorene
The covalent binding of an ultimate carcinogen to the DNA bases or phosphate groups creates a premutational lesion that in vivo is processed by the repair, replication and recombination enzymes, and eventually may be converted into a mutation. Being interested in the way that an initial premutationa...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
1983
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569123/ |