Chemosensitization by misonidazole in CCNU-treated spheroids and tumours.
Misonidazole has been demonstrated to enhance the cytotoxicity of several common antineoplastic drugs in vitro and in vivo, and its mechanism of action as a chemosensitizer, though still unknown, is thought to be dependent upon hypoxia. We have used fluorescence-activated cell sorting to evaluate ch...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
1987
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002149/ |