Oxygen dependence for chemosensitization by misonidazole.

Misonidazole (MISO) potentiates the cell killing effect of certain chemotherapy agents, but only under hypoxic conditions. The purpose of the present study was to define the range of oxygen concentrations over which chemosensitization by MISO takes place using mammalian cells cultured in vitro, and...

Full description

Bibliographic Details
Main Authors: Roizin-Towle, L., Hall, E. J., Pirro, J. P.
Format: Online
Language:English
Published: 1986
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001598/