The in vitro effects and cross-resistance patterns of some novel anthracyclines.
A range of new anthracyclines, structurally related to adriamycin (ADM), has been synthesised and studied in vitro. Three compounds described in this paper (Ro 31-1215; Ro 31-1741; Ro 31-2035) are all 4-demethoxyanthracyclines. In the mouse mammary tumour cell line, EMT6/Ca/VJAC, using a 1 h drug ex...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1986
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001391/ |