In vitro anthracycline cross-resistance pattern in childhood acute lymphoblastic leukaemia.

Daunorubicin (DNR) is a major front-line drug in the treatment of childhood acute lymphoblastic leukaemia (ALL). Previously, we showed that in vitro resistance to DNR at diagnosis is related to a poor long-term clinical outcome in childhood ALL and that relapsed ALL samples are more resistant to DNR...

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Bibliographic Details
Main Authors: Klumper, E., Pieters, R., den Boer, M. L., Huismans, D. R., Loonen, A. H., Veerman, A. J.
Format: Online
Language:English
Published: 1995
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033825/