Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells.
In tumour cells the pharmacological basis for multidrug resistance (MDR) often appears to be a reduced cellular cytostatic drug accumulation caused by the drug efflux protein, P-glycoprotein (Pgp MDR), or by other drug transporters (non-Pgp MDR). Here we report the reversal of the decreased daunorub...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1993
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968712/ |