Prevalence, clinical relevance and characterization of circulating cytotoxic CD4+CD28- T cells in ankylosing spondylitis

Prevalence, clinical relevance and characterization of circulating cytotoxic CD4+CD28- T cells in ankylosing spondylitis

Circulating CD3+CD4+CD28- cells exhibit reduced apoptosis and were found to be more enriched in patients with ankylosing spondylitis than in age-matched healthy control individuals (7.40 ± 6.6% versus 1.03 ± 1.0%; P < 0.001). Levels of CD4+CD28- T cells correlate with disease status as measured u...

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Bibliographic Details
Main Authors: Duftner, Christina, Goldberger, Christian, Falkenbach, Albrecht, Würzner, Reinhard, Falkensammer, Barbara, Pfeiffer, Karl P, Maerker-Hermann, Elisabeth, Schirmer, Michael
Format: Online
Language:English
Published: BioMed Central 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193730/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193730/

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