Between adaptive and innate immunity: TLR4-mediated perforin production by CD28null T-helper cells in ankylosing spondylitis

CD3+CD4+CD28null and CD3+CD8+CD28null T cells are enriched in patients with immune-mediated diseases compared with healthy controls. This study shows that CD4+CD28null T cells express Toll-like receptors recognizing bacterial lipopolysaccharides in ankylosing spondylitis, psoriatic arthritis and rhe...

Full description

Bibliographic Details
Main Authors: Raffeiner, Bernd, Dejaco, Christian, Duftner, Christina, Kullich, Werner, Goldberger, Christian, Vega, Sandra C, Keller, Michael, Grubeck-Loebenstein, Beatrix, Schirmer, Michael
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297589/