Surrogate Light Chain Expressing Human Peripheral B Cells Produce Self-reactive Antibodies
Human B cells that coexpress surrogate and conventional light chains (V-preB+L+) show an unusual heavy and light chain antibody repertoire that display evidence of receptor editing. However, it is unclear whether V-preB+L+ B cells have been silenced by receptor editing or still express autoreactive...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2004
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887722/ |