Inclusion of unaffected sibs increases power in model-free linkage analysis of a behavioral trait

Study design strategies are of critical importance in the search for genes underlying complex diseases. Two important design choices in planning gene mapping studies are the analytic strategy to be used, which will have an impact on the type of data to be collected, and the choice of genetic markers...

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Bibliographic Details
Main Authors: Plancoulaine, Sabine, Alcaïs, Alexandre, Chen, Yue, Abel, Laurent, Gagnon, France
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866764/