Linkage analysis of alcohol dependence using both affected and discordant sib pairs
The basic idea of affected-sib-pair (ASP) linkage analysis is to test whether the inheritance pattern of a marker deviates from Mendelian expectation in a sample of ASPs. The test depends on an assumed Mendelian control distribution of the number of marker alleles shared identical by descent (IBD),...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866749/ |