On different approximations to multilocus identity-by-descent calculations and the resulting power of variance component-based linkage analysis

An empirical comparison between three different methods for estimation of pair-wise identity-by-descent (IBD) sharing at marker loci was conducted in order to quantify the resulting differences in power and localization precision in variance components-based linkage analysis. On the examined simulat...

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Bibliographic Details
Main Authors: Göring, Harald HH, Williams, Jeff T, Dyer, Thomas D, Blangero, John
Format: Online
Language:English
Published: BioMed Central 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866511/