A variance component-based gene burden test
We propose a novel variance component approach for the analysis of next-generation sequencing data. Our method is based on the detection of the proportion of the trait phenotypic variance that can be explained by the introduction of a new variance component that accounts for the local gene-specific...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143638/ |