Genome-wide linkage analysis of longitudinal phenotypes using σ2A random effects (SSARs) fitted by Gibbs sampling

The study of change in intermediate phenotypes over time is important in genetics. In this paper we explore a new approach to phenotype definition in the genetic analysis of longitudinal phenotypes. We utilized data from the longitudinal Framingham Heart Study Family Cohort to investigate the famili...

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Bibliographic Details
Main Authors: Palmer, Lyle J, Scurrah, Katrina J, Tobin, Martin, Patel, Sanjay R, Celedon, Juan C, Burton, Paul R, Weiss, Scott T
Format: Online
Language:English
Published: BioMed Central 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866446/