Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis

Quantitative traits such as complex diseases are controlled by many small-effect genes that are difficult to identify. Here we present a novel strategy to identify the candidate genes for small-effect quantitative trait loci (QTL) in collagen induced arthritis (CIA) using global genome and transcrip...

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Bibliographic Details
Main Authors: Yu, Xinhua, Bauer, Kristin, Koczan, Dirk, Thiesen, Hans-Jürgen, Ibrahim, Saleh M
Format: Online
Language:English
Published: BioMed Central 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860061/