A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

Meganucleases, or homing endonucleases (HEs) are sequence-specific endonucleases with large (>14 bp) cleavage sites that can be used to induce efficient homologous gene targeting in cultured cells and plants. These findings have opened novel perspectives for genome engineering in a wide range of...

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Bibliographic Details
Main Authors: Smith, Julianne, Grizot, Sylvestre, Arnould, Sylvain, Duclert, Aymeric, Epinat, Jean-Charles, Chames, Patrick, Prieto, Jesús, Redondo, Pilar, Blanco, Francisco J., Bravo, Jerónimo, Montoya, Guillermo, Pâques, Frédéric, Duchateau, Philippe
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1702487/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1702487/

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