In vivo selection of engineered homing endonucleases using double-strand break induced homologous recombination
Homing endonucleases, endonucleases capable of recognizing long DNA sequences, have been shown to be a tool of choice for precise and efficient genome engineering. Consequently, the possibility to engineer novel endonucleases with tailored specificities is under strong investigation. In this report,...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Oxford University Press
2005
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289081/ |