The expansion of CD4+CD28- T cells in patients with rheumatoid arthritis

Clonal expansion of CD4+CD28- T cells is a characteristic finding in patients with rheumatoid arthritis (RA). Expanded CD4+ clonotypes are present in the peripheral blood, infiltrate into the joints, and persist for years. CD4+CD28- T cells are oligoclonal lymphocytes that are rare in healthy indivi...

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Bibliographic Details
Main Authors: Pawlik, Andrzej, Ostanek, Lidia, Brzosko, Iwona, Brzosko, Marek, Masiuk, Marek, Machalinski, Boguslaw, Gawronska-Szklarz, Barbara
Format: Online
Language:English
Published: BioMed Central 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165060/