Preneoplastic and neoplastic progression during hepatocarcinogenesis in mice injected with diethylnitrosamine in infancy.
Basophilic hepatic foci, nodules, and trabecular hepatocellular carcinomas, collectively referred to as focal hepatic lesions, were induced by single injections of 5.0 micrograms of diethylnitrosamine (DEN) per gram body weight in 15-day-old C57BL/6J X C3HeB/FeJ F1 (B6C3 F1) mice. Groups of eight ex...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1983
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569251/ |