Inhalation pharmacokinetics of 1,3-butadiene and 1,2-epoxybutene-3 in rats and mice.
Studies were conducted on inhalation pharmacokinetics of 1,3-butadiene and of its primary reactive metabolic intermediate 1,2-epoxybutene-3 in rats (Sprague-Dawley) and mice (B6C3F1). Investigations of inhalation pharmacokinetics of 1,3-butadiene revealed saturation kinetics of 1,3-butadiene metabol...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1990
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567735/ |