Species differences in the metabolism and disposition of inhaled 1,3-butadiene and isoprene.

Species differences in sensitivity to carcinogenic effects from inhaled 1,3-butadiene might stem, at least in part, from differences in uptake, metabolism, and distribution of 1,3-butadiene. To examine this possibility, rats, mice, and monkeys were exposed to stepped concentrations of 14C-labeled 1,...

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Bibliographic Details
Main Authors: Dahl, A R, Bechtold, W E, Bond, J A, Henderson, R F, Mauderly, J L, Muggenburg, B A, Sun, J D, Birnbaum, L S
Format: Online
Language:English
Published: 1990
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567764/