Effect of enzyme induction on nephrotoxicity of halothane-related compounds.
Nephrotoxicity following administration of methoxyflurane has been shown to be directly related to anesthetic metabolism to inorganic fluoride. Enzyme induction should increase metabolic rate and the amount of inorganic fluoride that is released. In vivo studies in Fischer 344 rats show that enzyme...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
1977
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475347/ |