Experimental induction of ovarian Sertoli cell tumors in rats by N-nitrosoureas.

Spontaneous ovarian tumors are very rare in ACI, Wistar, F344 and Donryu rats; the few neoplasms found are of the granulosa/theca cell type. Ovarian tumors were also rare in these strains of rats when given high doses of N-alkyl-N-nitrosoureas continuously in the drinking water for their life-span;...

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Bibliographic Details
Main Authors: Maekawa, A, Onodera, H, Tanigawa, H, Furuta, K, Kanno, J, Ogiu, T, Hayashi, Y
Format: Online
Language:English
Published: 1987
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474567/