Comparative evaluation of genetic toxicity patterns of carcinogens and noncarcinogens: strategies for predictive use of short-term assays.

The results of a recent comprehensive evaluation of the relationship between four measures of in vitro genetic toxicity and the capacity of the chemicals to induce neoplasia in rodents carry some important implications. The results showed that while the Salmonella mutagenesis assay detected only abo...

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Bibliographic Details
Main Authors: Tennant, R W, Spalding, J W, Stasiewicz, S, Caspary, W D, Mason, J M, Resnick, M A
Format: Online
Language:English
Published: 1987
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474441/