Algorithm for automatic genotype calling of single nucleotide polymorphisms using the full course of TaqMan real-time data

Algorithm for automatic genotype calling of single nucleotide polymorphisms using the full course of TaqMan real-time data

Single nucleotide polymorphisms (SNPs) are often determined using TaqMan real-time PCR assays (Applied Biosystems) and commercial software that assigns genotypes based on reporter probe signals at the end of amplification. Limitations to the large-scale application of this approach include the need...

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Bibliographic Details
Main Authors: Callegaro, A., Spinelli, R., Beltrame, L., Bicciato, S., Caristina, L., Censuales, S., De Bellis, G., Battaglia, C.
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440877/

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