Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles

Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles

A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three- component condensation of aldehydes, amines, and potassium cyanide in acetonitrile in the presence of a catalytic amount of CoCl2 at room temperature.

Bibliographic Details
Main Author:	De, Surya K
Format:	Online
Language:	English
Published:	BioMed Central 2005
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399456/

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