Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles
A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three- component condensation of aldehydes, amines, and potassium cyanide in acetonitrile in the presence of a catalytic amount of CoCl2 at room temperature.
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| Format: | Online |
| Language: | English |
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BioMed Central
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399456/ |