Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals.
In vitro work in this laboratory has identified new DNA lesions resulting from further oxidation of a common biomarker of oxidative damage, 8-oxo-7,8-dihydroguanine (OG). The major product of oxidation of OG in a nucleoside, nucleotide, or single-stranded oligodeoxynucleotide using metal ions that a...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2002
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241231/ |