Secondary structural characterization of oligonucleotide strands using electrospray ionization mass spectrometry
Differences in charge state distributions of hairpin versus linear strands of oligonucleotides are analyzed using electrospray ionization mass spectrometry (ESI-MS) in the negative ion detection mode. It is observed that the linear structures show lower charge state distribution than the hairpin str...
Main Authors: | Guo, Xinhua, Bruist, Michael F., Davis, Darryl L., Bentzley, Catherine M. |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1164437/ |
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