Secondary structural characterization of oligonucleotide strands using electrospray ionization mass spectrometry

Differences in charge state distributions of hairpin versus linear strands of oligonucleotides are analyzed using electrospray ionization mass spectrometry (ESI-MS) in the negative ion detection mode. It is observed that the linear structures show lower charge state distribution than the hairpin str...

Full description

Bibliographic Details
Main Authors: Guo, Xinhua, Bruist, Michael F., Davis, Darryl L., Bentzley, Catherine M.
Format: Online
Language:English
Published: Oxford University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1164437/