An Immune Basis for Malaria Protection by the Sickle Cell Trait

In a Kenyan population, protection against malaria by sickle cell trait increased over the first 10 years of life, suggesting that the mechanism of protection involves acquired immunity to the parasite.

Bibliographic Details
Main Authors: Williams, Thomas N, Mwangi, Tabitha W, Roberts, David J, Alexander, Neal D, Weatherall, David J, Wambua, Sammy, Kortok, Moses, Snow, Robert W, Marsh, Kevin
Format: Online
Language:English
Published: Public Library of Science 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140945/
id pubmed-1140945
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spelling pubmed-11409452005-05-31 An Immune Basis for Malaria Protection by the Sickle Cell Trait Williams, Thomas N Mwangi, Tabitha W Roberts, David J Alexander, Neal D Weatherall, David J Wambua, Sammy Kortok, Moses Snow, Robert W Marsh, Kevin Research Article In a Kenyan population, protection against malaria by sickle cell trait increased over the first 10 years of life, suggesting that the mechanism of protection involves acquired immunity to the parasite. Public Library of Science 2005-05 2005-05-31 /pmc/articles/PMC1140945/ /pubmed/15916466 http://dx.doi.org/10.1371/journal.pmed.0020128 Text en Copyright: © 2005 Williams et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Williams, Thomas N
Mwangi, Tabitha W
Roberts, David J
Alexander, Neal D
Weatherall, David J
Wambua, Sammy
Kortok, Moses
Snow, Robert W
Marsh, Kevin
spellingShingle Williams, Thomas N
Mwangi, Tabitha W
Roberts, David J
Alexander, Neal D
Weatherall, David J
Wambua, Sammy
Kortok, Moses
Snow, Robert W
Marsh, Kevin
An Immune Basis for Malaria Protection by the Sickle Cell Trait
author_facet Williams, Thomas N
Mwangi, Tabitha W
Roberts, David J
Alexander, Neal D
Weatherall, David J
Wambua, Sammy
Kortok, Moses
Snow, Robert W
Marsh, Kevin
author_sort Williams, Thomas N
title An Immune Basis for Malaria Protection by the Sickle Cell Trait
title_short An Immune Basis for Malaria Protection by the Sickle Cell Trait
title_full An Immune Basis for Malaria Protection by the Sickle Cell Trait
title_fullStr An Immune Basis for Malaria Protection by the Sickle Cell Trait
title_full_unstemmed An Immune Basis for Malaria Protection by the Sickle Cell Trait
title_sort immune basis for malaria protection by the sickle cell trait
description In a Kenyan population, protection against malaria by sickle cell trait increased over the first 10 years of life, suggesting that the mechanism of protection involves acquired immunity to the parasite.
publisher Public Library of Science
publishDate 2005
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140945/
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