Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes

Plasmodium falciparum infections can cause severe malaria, but not every infected person develops life-threatening complications. In particular, carriers of the structural haemoglobinopathies S and C and infants are protected from severe disease. Protection is associated with impaired parasite-induc...

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Bibliographic Details
Main Authors: Cyrklaff, Marek, Srismith, Sirikamol, Nyboer, Britta, Burda, Kvetoslava, Hoffmann, Angelika, Lasitschka, Felix, Adjalley, Sophie, Bisseye, Cyrille, Simpore, Jacques, Mueller, Ann-Kristin, Sanchez, Cecilia P., Frischknecht, Friedrich, Lanzer, Michael
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105170/