Analysis of genetic factors influencing alpha-defensin gene expression

Background: The DEFA1A3 locus on chromosome 8p23.1 has been known to exhibit copy number variation (between 3 and 16 copies) and to include either the DEFA1 gene or the DEFA3 gene in any repeat. These two genes encode the Human Neutrophil Peptides HNPs 1-3, antimicrobial peptides implicated in the i...

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Bibliographic Details
Main Author: Necsoiu, Paula Eugenia
Format: Thesis (University of Nottingham only)
Language:English
Published: 2018
Online Access:http://eprints.nottingham.ac.uk/50661/
http://eprints.nottingham.ac.uk/50661/1/PAULA%20NECSOIU%20THESIS%20revised.pdf