Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology
Human induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs) have applications in disease modeling, cell therapy, drug screening and personalized medicine. Computational models can be used to interpret experimental findings in iPSC-CMs, provide mechanistic insights, and translate these find...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Research Foundation
2017
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| Online Access: | http://eprints.nottingham.ac.uk/48668/ http://eprints.nottingham.ac.uk/48668/ http://eprints.nottingham.ac.uk/48668/ http://eprints.nottingham.ac.uk/48668/1/Lei-et-al-2017%20tailored%20stem%20cell%20derived%20myocyte%20models.pdf |