The antimalarial drug quinine interferes with serotonin biosynthesis and action
The major antimalarial drug quinine perturbs uptake of the essential amino acid tryptophan, and patients with low plasma tryptophan are predisposed to adverse quinine reactions; symptoms of which are similar to indications of tryptophan depletion. As tryptophan is a precursor of the neurotransmitter...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2014
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| Online Access: | http://eprints.nottingham.ac.uk/40885/ http://eprints.nottingham.ac.uk/40885/ http://eprints.nottingham.ac.uk/40885/ http://eprints.nottingham.ac.uk/40885/1/Islahudin%20et%20al%20%282014%29%20Nature%20Sci.%20Rep.%20published%20pdf.pdf |