Cell wall perturbation sensitizes fungi to the antimalarial drug chloroquine

Chloroquine (CQ) has been a mainstay of antimalarial drug treatment for several decades. Additional therapeutic actions of CQ have been described, including some reports of fungal inhibition. Here we investigated the action of CQ in fungi, including the yeast model Saccharomyces cerevisiae. A genome...

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Bibliographic Details
Main Authors: Islahudin, Farida, Khozoie, Combiz, Bates, Steven, Ting, Kang-Nee, Pleass, Richard J., Avery, Simon V.
Format: Article
Language:English
Published: American Society for Microbiology 2013
Online Access:http://eprints.nottingham.ac.uk/2343/
http://eprints.nottingham.ac.uk/2343/
http://eprints.nottingham.ac.uk/2343/
http://eprints.nottingham.ac.uk/2343/1/Avery_Cell_Wall.full.pdf