Investigating splicing variants uncovered by next-generation sequencing the Alzheimer’s disease candidate genes, CLU, PICALM, CR1, ABCA7, BIN1, the MS4A locus, CD2AP, EPHA1 and CD33

Investigating splicing variants uncovered by next-generation sequencing the Alzheimer’s disease candidate genes, CLU, PICALM, CR1, ABCA7, BIN1, the MS4A locus, CD2AP, EPHA1 and CD33

Late onset Alzheimer’s disease (LOAD), the most common cause of late onset dementia, has a strong genetic component. To date, 21 disease-risk loci have been identified through genome wide association studies (GWAS). However, the causative functional variant(s) within these loci are yet to be discove...

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Main Authors: Clement, Naomi, Braae, Anne, Turton, James, Lord, Jenny, Guetta-Baranes, Tamar, Medway, Christopher, Brookes, Keeley, Barber, Imelda S., Patel, Tulsi, Milla, Lucy, Azzopardi, Maria, Lowe, James, Mann, David, Pickering-Brown, Stuart, Kalsheker, Noor, Passmore, Peter, Chappell, Sally, Morgan, Kevin
Format: Article
Language:English
Published: OMICS International 2016
Online Access:http://eprints.nottingham.ac.uk/38399/
http://eprints.nottingham.ac.uk/38399/
http://eprints.nottingham.ac.uk/38399/
http://eprints.nottingham.ac.uk/38399/1/2161-0460-6-276.pdf

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http://eprints.nottingham.ac.uk/38399/
http://eprints.nottingham.ac.uk/38399/
http://eprints.nottingham.ac.uk/38399/
http://eprints.nottingham.ac.uk/38399/1/2161-0460-6-276.pdf

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